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Published Study: Functional Properties of Bacillus subtilis DE111

Collective research on the genetic and mechanistic abilities of the probiotic DE111® has been published in Frontiers of Microbiology.  This work, entitled “In vitro and in silico assessment of probiotic and functional properties of Bacillus subtilis DE111®”, supports the demonstration…

Human Clinical Study: DE111 Germinates in the Small Intestine

While probiotic spores can confer health benefits, it is believed that germination of the spores is required for some probiotic activity (i.e. short chain fatty acids, antimicrobial peptides, enzymes, etc.). A novel clinical trial in 11 ileostomy participants was conducted…

Human Clinical Study: DE111 Supports Digestion

A clinical study evaluating the effect of DE111 on digestive health resulted in a significant influence on gut microbiota measured prior to and after capsule consumption (5 billion CFU). Fecal samples showed an increase in the levels of B. subtilis…